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More serious considerations include risk of pancreatitis, gallbladder problems, kidney injury (often related to dehydration from gastrointestinal symptoms), and rare cases of medullary thyroid cancer (these medications carry a black box warning for patients with personal or family history of MTC or MEN2 syndrome)

Lancet Diabetes Endocrinol 9: 653662, 2021

These symptoms may indicate complications requiring medical assessment

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