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Description
In contrast to macrovascular disease, neuropathy often develops silently before symptoms appear
These include Alzheimers disease, Parkinsons disease and alcohol use disorder (Figure 2)
Importantly, this concept does not imply overt NAD depletion
and reporting of cardiovascular or renal outcomes
Carleton A, Accolla R, Simon SA
Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase
