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After a dose-titration and dose-stable run-in period of up to 16 weeks and a 2-week placebo run-in period, patients with inadequate glycemic control (A1C 7.5% to 10.5%) were randomized to the addition of either 100 mg of JANUVIA or placebo, administered once daily

Pacheco-Pantoja EL, Ranganath LR, Gallagher JA, Wilson PJ, Fraser WD

Ozempic is a GLP-1 medication developed to help patients diagnosed with diabetes

19-22 GLP-1 receptor agonists GLP-1 receptor agonists continue to grow in popularity for the treatment of T2DM due to their beneficial effects on glycemia and weight

This means AUD is not just a disease of the brain, but the gut may be involved too

Clinical trial data provides objective evidence about efficacy (24.2% weight loss at 48 weeks), safety (88.8% completion rate), side effects (peak at weeks 6-8, resolve by week 12 for most), and discontinuation outcomes (70-80% regain over 12-18 months, not immediately)