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By limiting the most probable DPP-8-selectivity imparting modification points in DPP-8/9 inhibitors to areas of space that are topologically similar to the piperazine ring, this strategy may serve as a useful platform for developing future selective DPP-8 inhibitors, including novel chemotypes

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C.et al (2015)

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After 4 doses, throw away (discard) the Pen, including the unused medicine

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Symptoms are most likely to appear during dose increases or near the target dose and often improve as the body adjusts over time

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95% confidence interval (CI), 1.231.52)

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