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August 1, 2025: People Who Experienced Vision Loss from Trulicity May Have New Legal Options Trulicity and other GLP-1 drugs can put people at an increased risk of a serious eye condition called NAION (non-arteritic anterior ischemic optic neuropathy), which can cause permanent blindness

The Salk researchers suspect this longer-term presence may explain some of the wonder drug benefits of GLP-1 drugs

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In addition to its peptidase activity, DPP4 participates in adenosine deaminase binding, cell matrix adhesion, the migration and invasion of endothelial cells into collagenous matrices, co-stimulation during T cell activation, and interaction with human immunodeficiency virus (HIV) proteins