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36 months: Many people lose around 510% of their starting body weight

Additionally, chronic versus acute allulose consumption may produce different effects, as repeated exposure could lead to adaptive changes in gut hormone secretion patterns, though longitudinal data addressing this question are currently lacking

doi: 10.1053/j.gastro.2013.04.006 61 ChangLSultanSLemboAVerneGNSmalleyWHeidelbaughJJ

Estimation of clinical trial success rates and related parameters