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For weekly medications, the timing has less impact on side effects due to their steady-state pharmacokinetics

For monitoring of individuals taking GLP-1s, DXA could be considered yearly or every two years, yet such a timeline may impede the identification of early muscle loss and the institution of appropriate interventions

The case series data mentioned above, where one patient lost 33 percent of their body weight with 91 percent of the loss coming from fat, included consistent resistance training as a core component of the protocol

More mentally clear and less wiped out

Diabetes 61 , 12501262 (2012)

Not to get too deep into the science, but a PPAR agonist delivered selectively because of GLP1 and GIP receptors may mean that we can see the insulin sensitizing benefit of this drug class without the negative side effects that prior meds in this class have suffered from