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Review article: a comparison of glucagon-like peptides 1 and 2

Semaglutide-based drugs Ozempic and Wegovy, and the tirzepatide-based Mounjaro have been everywhere

You can also take rodents and create alpha-synuclein deposits of Lewy body, you can knock out their dopamine system, your area of expertise with MPTP, and create a Parkinsons model

Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, et al

Therapeutic Indications and Dosing Protocols Among GLP-1 receptor agonists approved for weight management, liraglutide (SAXENDA) is one of the earliest agents to receive authorization from both the FDA and EMA

However, the complexities and barriers present in the in vivo environment still present ongoing challenges for the optimal design of peptide-based targeting moieties: (1) Conventional peptide ligands are susceptible to enzymatic barriers