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The next-generation therapy combines semaglutide with cagrilintide, a long-acting analog of amylin, which is a pancreatic peptide that lowers blood glucose levels and slows down gastric emptying

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2.6 Protein extraction and standardization The hippocampal tissues from the mice were well ground with liquid nitrogen, removed into a 1.5-mL centrifuge tube, made to a final concentration of 1 mM with a protease inhibitor (Biotech, A610425-0005) and phosphatase inhibitor (Roche, 4906837001), followed by lysing by sonication (SCIENTZ-II D)

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