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This period is expected to be characterized by expansion of public reimbursement programs in major European and Asian markets, maturation of cardiovascular-anchored treatment protocols, and broader adoption across middle-income countries

IRS, insulin receptor substrate

Cardiovascular, mortality, and kidney outcomes with GLP1 receptor agonists in patients with type 2 diabetes: A systematic review and metaanalysis of cardiovascular outcome trials

Among those with obesity, GLP-1RA users demonstrated a 47% reduced risk of pancreatic cancer versus insulin users, and a 19% lower risk compared to those taking SGLT2 inhibitors

[DOI] [PMC free article] [PubMed] [Google Scholar] 518.Sarson D.L., Scopinaro N., Bloom S.R

Cost and administration also differ significantly