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Weight management is a long-term endeavour, and medication is most effective when combined with sustained lifestyle changes

Wegovy FDA approvals: In June 2021, the FDA approved Wegovy to combat obesity and promote weight loss in adults who are obese or overweight with at least one weight-related health condition

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Beta-blocker use, including propranolol, is classified as a relative contraindication to subcutaneous allergen immunotherapy (SCIT) by the British Society for Allergy and Clinical Immunology (BSACI), because it may both increase the risk of a systemic reaction and reduce the effectiveness of adrenaline used to treat one

Implications for weight loss drugmakers: Lilly and Novos battle across injectables and pills will define how the category evolves, and raise the bar for new entrants