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Indeed, local Ex4 infusion into the LDTg suppresses alcohol-induced locomotor stimulation, dopamine release in the NAc, memory of alcohol reward, and alcohol drinking in male rodents (Vallof et al., 2019a)

, Paulsen, S

Glucagon-like peptide-1 receptor agonists (GLP-1RAs), notably the long-acting agonist semaglutide, exhibit significant metabolic efficacy and pronounced neuroprotective effects across a broad spectrum of preclinical models

This narrative review synthesizes preclinical, clinical, and real-world evidence evaluating the therapeutic potential of GLP-1RAs in BD

The generic terms may be less familiar, but the first really powerful GLP-1 receptor agonist, or stimulant, was semaglutide

doi: 10.1056/nejmoa2511774