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But knowing what to expect, and how to manage it, makes the experience dramatically more tolerable

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Garvey WT, Frias JP, Jastreboff AM, et al

Doctors may also prescribe it off-label for weight loss in specific situations, but this is decided on a case-by-case basis

Constipation: While some patients experience diarrhea, others may find that digestion slows too much, leading to constipation

Carbonated beverages: The gas adds to the bloating that delayed emptying already creates

Effects when activated: Stimulate insulin secretion from pancreatic beta cells Inhibit glucagon secretion from pancreatic alpha cells Slow gastric emptying Increase satiety (feeling of fullness) Potential neuroprotective effects in the brain GIP Receptors: Function: GIP (Glucose-dependent Insulinotropic Polypeptide) receptors respond to the hormone GIP
