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Noria SF, Shelby RD, Atkins KD, et al

In fact, now is the perfect time to focus on balanced eating that supports your long-term goals and lifestyle

GLP-1 receptor agonists demonstrate efficacy in modulating reward pathway dysfunction by normalizing insulin resistance and stabilizing glycemic variability, thereby reducing cravings and subsequently suppressing appetite [134]

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Nevertheless, more studies in various models of cardiometabolic disease are needed to confirm the cardioprotective mechanisms, especially considering that there is limited evidence available to elucidate the mechanistic details regarding the cardiovascular biology or long-term safety of selective GIPR agonism in humans (Hammoud & Drucker 2023)

At the genus level, liraglutide administration significantly reduced Ruminococcus and did not increase Akkermansia (Supplementary Fig