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In the largest clinical trial that tested Wegovy before its FDA approval, people taking the highest dose (2.4 milligrams) lost, on average, more than 12% of their body weight over 17 months

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NEP 24.11 (neutral endopeptidase 24.11, also known as Neprilysin, CD10, MME and CALLA) is an unspecific membrane protease that quickly cleaves GLP-1 at multiple sites 35

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First, more Medicaid enrollees are being prescribed GLP-1s for obesity