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While not FDA-approved as a finished product, compounded semaglutide has the same active ingredient and bioavailability as brand versions, at a significantly lower cost

Clinical trials and safety studies show that serious liver problems from semaglutide are uncommon

Research questions include whether GLP-3 affects body composition differently than GLP-1, potentially preserving more muscle mass during weight loss, if GLP-3 enhances fat oxidation and metabolic rate through distinct pathways, whether combining GLP-3 with GLP-1 approaches offers advantages over either alone, and how GLP-3 might benefit metabolic flexibility and long-term weight maintenance

Mounjaro can cause acute gallbladder disease