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Nevertheless, these co-agonists must be carefully monitored as a loss in GLP-1R activity could lead to excessive glucagon-mediated deleterious effects on glucose control

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[8] GLP-1 agonists & Dual GIP/GLP-1 receptor agonists With the significant efficacy of GLP-1 therapy in weight reduction and diabetes management, the potential of such therapy for treating NASH has garnered attention, leading to the initiation of many relevant trials

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Effect estimates remained robust when restricting to patients with available hemoglobin A1c and including it in the propensity score (Supplementary Table 23)