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However, the concentrations of liraglutide were significantly different in the different brain regions following IV injection

In this issue of Diabetologia, Kang et al (DOI: 10.1007/s00125-012-2776-x ) provide evidence that in addition to glucotoxicity, lipotoxicity also affects incretin receptor expression and signalling in insulin-secreting cells and isolated islets

GLP-1 is essential for appetite regulation Your gut naturally produces GLP-1, the 'un-hunger' hormone that plays multiple roles in metabolic health