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Hydration strategies are critical, particularly for patients experiencing vomiting or diarrhea
[8] [9] Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish over time with dose titration

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Retatrutide , a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, showed up to 24.2% body weight reduction in Phase 2 trials

Loss of activity indicates structural damage during reconstitution or storage

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