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Common menstrual changes reported with Zepbound use People on Zepbound, Wegovy, or other GLP-1/GIP medications report several notable side effects specifically related to menstruation

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Taken together, these pharmacokinetic findings indicate that the centrally mediated effects of GLP-1RAs are likely due to limited brain penetration or action at sites adjacent to the BBB, rather than widespread distribution throughout the central nervous system

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Mounjaro received FDA approval in 2022 for the treatment of type 2 diabetes in adults