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Pathophysiology of IIH The dysregulation of CSF dynamics is thought to play a significant role in the pathophysiology of IIH, which may involve overproduction of CSF by the choroid plexus, reduced reabsorption via AGs, venous outflow obstruction, and overflow of the glymphatic system (Fig

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Added to this there were already a number of antihistamines on the market for suppressing allergic reactions like hayfever, but these had no impact on the secretion of stomach acid

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This data suggests that around 3 billion people are living with either obesity or overweight

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