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We therefore conducted systematic sensitivity analyses to examine result robustness, comprising: One-way sensitivity analysis: Individual variation of critical parameters to quantify their isolated impact on outcomes

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This step is essential in research, therapeutic applications, and experimental use, as it ensures peptides maintain their biological activity

Median duration of gastrointestinal side effects on semaglutide 2.4 mg: nausea 8 days, vomiting 2 days, diarrhoea 3 days, constipation 47 days