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Description
Common adverse effects include: Nausea (reported by 30-40% of patients at the 2.4 mg dose) Vomiting Diarrhea Constipation Abdominal pain Decreased appetite These gastrointestinal symptoms are typically most pronounced during dose escalation and often improve with continued treatment

Less common but more serious potential side effects include pancreatitis, gallbladder problems, and changes in kidney function

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Patients with very high triglycerides require urgent medical attention: same-day assessment if triglycerides 20 mmol/L or if pancreatitis symptoms are present, and urgent specialist referral if triglycerides 10 mmol/L

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The maintenance dose is individualized based on response and tolerability
