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REIMAGINE 2 was a 68-week efficacy & safety trial investigating once weekly SC CagriSema, a fixed-dose combination of the Amylin receptor agonist, cagrilintide, & GLP-1RA, Semaglutide, compared to Semaglutide & placebo, the study enrolled 2,728 patients with type 2 diabetes inadequately controlled with metformin with or without an SGLT2I
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However, comparative data evaluating the effectiveness of both options for the management of RWG after primary MBS remain limited
But so far, there has been comparatively less research on what happens when users stop taking the drugs.
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