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Description
R.TreichelA

Hypothalamic GPCR signaling pathways in cardiometabolic control

Drug Saf

GLP-1 RA treatment has been reported to increase irisin levels in patients with obesity and T2D

Although data from early phase trials suggest that retatrutide is well tolerated with a similar adverse event profile to GLP-1 RAs, additional research assessing long-term safety and efficacy of retatrutide in people living with obesity and/or T2D (including cardiovascular outcomes) is awaited over the next five years
Digestive side effects are common, particularly when starting treatment
