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GLP-1 RAs are an important consideration for use in type 2 diabetes where CKD has been identified, as they bring both CV and renal benefits (ADA, 2025)

In short, no, you should not stop taking tirzepatide if you are concerned about getting pregnant, says McBane
Tirzepatide w/niacinimide and Semaglutide w/niacinimide effects on birth control

However, most research is required to confirm this effect

This initial dose sets the foundation for the treatment and ensures that the body can tolerate Zepbound (tirzepatide) effectively