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Retrospective cohorts provide real-world insights but are limited by confounding, misclassification of exposure timing, and incomplete reporting of early pregnancy losses

00:23:11 Don Weinberger: Sure

There are all these different potential mechanisms of action, which are all basically just that they help neurons to survive, Rascol says

Constipation Constipation is another common side effect that, unlike nausea, often persists throughout treatment

The most promising compounds, 39 and 40 (Figure 6), showed an IC 50 of 2.80 nM against DPP-4 catalytic activity, with 20 - 40-fold selectivity over the DPP-8 and DPP-9 isozymes

Rittig et al