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The renal pelvis was cannulated with a 32 G triple-lumen catheter (ReCathCo, Allison Park, PA) via the ureter for intrapelvic perfusion and withdrawal of infusate and monitoring of pelvic pressure

The key principle is maintaining approximately seven-day intervals between doses rather than hitting an exact calendar date

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Other interventions, like non-surgical or surgical skin tightening procedures, can be helpful complements, too