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The recently initiated large-sized FLOW trial investigating the effects of semaglutide on hard renal outcomes in patients with DKD will provide clarity whether GLP-1 receptor agonists may reduce the burden of DKD in addition to their other beneficial metabolic and cardiovascular effects.

This infographic outlines the use of semaglutide in tablet form, specifically focusing on its mechanism as a GLP-1 receptor agonist that increases insulin, increases satiety, slows gastric emptying, and reduces glucagon.

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GLP-1R agonist 2 has the potential for research in metabolic diseases such as type 2 diabetes and obesity