how does a glp 1 receptor agonist work GLP-1 Agonists For Obesity In Non-Diabetic Patients: Game Changer Or Overhyped? Critical Analysis GlobalRPH What is GLP-1 and Its

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GLP-1 also contributes to reduced appetite by inducing a sense of satiety and inhibits gastric acid secretion, beneficial in conditions of excess gastric acidity

The bottom line: Our findings suggest that GLP-1RA and SGLT2i (and especially SGLT2i with the lowest number needed to treat (NNT) for nearly all study outcomes) may be the preferred glucose-lowering agents for cardiovascular risk reduction in patients at moderate risk for CVD, building on and consistent with existing RCT evidence in the high-risk population. This report highlights potential preference for GLP-1 drugs as a first-line treatment for Type 2 diabetes related to its cardioprotective effect

doi: 10.1016/j.japh.2023.10.002

[DOI] [PMC free article] [PubMed] 8.Cannon B, Nedergaard J

Available from: Kosiborod MN, Bhatta M, Davies M, Deanfield JE, Garvey WT, Khalid U, Kushner R, Rubino DM, Zeuthen N, Verma S