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However, seek urgent medical advice if you experience severe or persistent GI symptoms or acute abdominal pain

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Some patients escalate more slowly due to side effects, while others may accelerate slightly if tolerance is excellent

The sharp increase in demand has caused shortages, prompting both companies to continually expand their capacity to meet the rising needs

1 HF is commonly categorised according to left ventricular ejection fraction ranges into HF with reduced ejection fraction (HFrEF), HF with mildly reduced ejection fraction (HFmrEF) and HF with preserved ejection fraction (HFpEF), each of which has distinct possible pathophysiological mechanisms