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doi: 10.4103/ijem.IJEM_185_19

Semaglutide and Tirzepatide Maintenance Dose: Keeping Weight Off After GLP-1 Success Reaching your goal weight while on GLP-1 medications represents a significant milestone in your weight loss journey, but it also marks the beginning of a new phase that many patients find themselves navigating without clear guidance

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Sleep deprivation and chronic stress elevate cortisol levels, which blunt GLP-1 response and disrupt appetite control

Reduced intake and absorption can lead to deficiency, causing fatigue and brain fog

For patients with diabetes who are also taking insulin or sulfonylureas, monitoring for hypoglycemia is essential, and dose adjustments of these medications may be necessary