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TrimRx operates on this model, offering consultations with licensed providers who specialize in weight management

Go Straight to the Manufacturer Pharmaceutical companies like Eli Lilly and Novo Nordisk run their own direct pricing programs (LillyDirect for Zepbound and NovoCare for Wegovy) that allow eligible patients to purchase medication directly

113 This could be the paradigm in which GLP-1RAs are indicated for MASLD with complications

Patient-reported outcomes data from clinical trials in Japanese patients indicated that patients considered less frequent injections more convenient and flexible (51) and that their use led to an improvement in quality of life, without compromising glycemic control (52)

The Trump administration announced initiatives in November 2025 to expand GLP-1 access for Medicare beneficiaries with obesity plus significant comorbidities, with implementation expected around mid-2026