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Some studies found that GLP-1 receptor stimulation reduced anxiety-like behaviors during alcohol withdrawal and decreased relapse-like drinking patterns

In the TRIUMPH-1 trial, the 4 mg dose had a lower discontinuation rate due to adverse events than even placebo, suggesting that lower doses are well-tolerated

26 For observational studies we assessed the risk of bias following the Newcastle-Ottawa Scale that evaluates selection of participants, comparability of groups, and outcome assessment 27 (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 261.Punjabi M., Arnold M., Ruttimann E., Graber M., Geary N., Pacheco-Lopez G

Enetic drug target validation using Mendelian randomisation
