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In the USA, national surveillance of emergency department visits and hospital admissions suggests a rate of 28 cases per 1000 adults with diabetes per year, with a worrisome increase in emergency department visits and admissions for DKA seen since 2009 [209]

Freezing can alter the protein structure of the medication, making it less effective

A radioactive tracer is injected into the skin between the toes or fingers and imaging is used to visualize how well the lymphatic function

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