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For clinicians managing patients with both metabolic conditions and substance use history, the emerging data on GLP-1 receptor agonists present both opportunities and uncertainties

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Materials and Methods: A systematic literature search was conducted using PubMed, Google Scholar and Science Direct, including studies published up to 30 September 2024

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In native glucagon, the His1 residue participates directly in receptor binding and signal transduction at the glucagon receptor

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