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Makaronidis has received institutional funding from Novo Nordisk and Rhythm Pharmaceuticals, and research funding from the NIHR, the Sir Jules Thorne Charitable Trust and the Society for Endocrinology (UK)

Metformin: Why It Became the Gold Standard Metformin has earned its first-line position in diabetes treatment through decades of proven effectiveness, safety data, and affordability

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Do not take Rybelsus if you: Are allergic to semaglutide or any other ingredients in the medication Are pregnant or breastfeeding Have medullary thyroid cancer (MTC) Have multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Before taking Rybelsus, inform your doctor if you: Are pregnant or breastfeeding Ever had pancreatitis Have medullary thyroid cancer (MTC) or multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Have type 1 diabetes, develop ketoacidosis (increased ketones in blood or urine) Have a high heart rate Have end-stage renal disease or liver disease Have diabetic retinopathy Have digestive problems like vomiting, diarrhea or dehydration Drug interactions Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines

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Novo Nordisk Announces FDA Approval of Label Update for Rybelsus (semaglutide) Allowing Use as a First-Line Option for Adults With Type 2 Diabetes