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Description
In several RCTs, GLP-1RAs, when used alone or in combination with other hypoglycemic agents including metformin, sulfonylurea, DPP-4 inhibitor, thiazolidinedione, and sodium-glucose cotransporter 2 inhibitor, showed superior or non-inferior blood glucose lowering ability compared to insulin treatment [64,65]

Food and Drug Administration and request approval for orforglipron as a treatment for obesity by the end of 2025

So far only one oral GLP-1 has appeared on the market, in 2019

Supplementary data Supplementary data are available at Human Reproduction Open online

Blood Pressure-Lowering Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists

Differences in the study populations, treatment duration and adherence to the different GLP-1RA regimens might have contributed to the variations observed
