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doi: 10.1345/aph.1H060 121 HeimburgerSMBrondenAJohansenNJDejgaardTFVilsbollTKnopFK

The therapeutic success of GLP-1 RAs stems from their ability to target fundamental physiological processes underlying metabolic dysfunction while maintaining a favorable safety profile relative to older antidiabetic medications [3,4]

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The growth in the historic period can be attributed to rising prevalence of type 2 diabetes, increased awareness of glycemic control therapies, strong clinical efficacy versus traditional antidiabetics, physician preference for incretin-based therapies, favorable reimbursement in developed markets