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Key methodological challenges limiting causal inference include confounding by indication, whereby depression itself is a robust risk factor for dementia (hazard ratio approximately 2.0) and residual confounding persists despite the use of propensity score methods

New England Journal of Medicine, 384(11), 9891002.

for individuals 65 and older

Because of this, scientists are investigating whether these medications could influence mental health in some patients

Prescription costs have also risen 1315% on averagewith GLP-1s accounting for 20% of total prescription costs

The combination of improved clinical outcomes and economic incentives has solidified obesity therapeutics as a central pillar of modern healthcare strategy