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Vitamin C in high doses Vitamin C has osmotic laxative properties at high doses (1,000-2,000mg)

Mechanistically, C3G activated the PPAR/--catenin-TCF-4 pathway in STC-1 cells, enhancing PG precursor transcription and GLP-1 synthesis.Inhibiting PPAR/ with GSK0660 blocked this C3G-induced upregulation

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