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Lastly, the systemic effects of GLP-1RAs, such as body weight loss [103] and potential reduction in muscle mass [104], pose significant challenges for elderly individuals with neurodegenerative diseases

Growing evidence suggests that these agents may exert clinically significant effects beyond metabolic pathways as their use continues to expand across diverse patient populations [3]

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Over time, high blood sugar levels can damage the nerves and blood vessels, leading to severe complications