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Activation of GLP-1R also triggers the PI3K/Akt signaling pathway via the subunits of G proteins, thereby promoting -cell viability and replicative capacity ( 2.2 Inflammation and immune modulation Recent preclinical studies have demonstrated its bidirectional immunomodulatory effects, including improvement of organ dysfunction, regulation of immune responses, and mitigation of sepsis-associated cytokine storms, mediated through anti-inflammatory and anti-apoptotic pathways

Among young adults with overweight or obesity in the general population, nearly 29% of women and 15% of men reported disordered eating behaviors

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Data collection Semi-structured individual interviews were conducted with participants 1216 weeks after starting GLP-1 receptor agonist, to explore experiences of the impact on mental health

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