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It doesn't meaningfully engage the body's energy expenditure side of the equation

A Timeline of GLP-1 Medications 1971 Jens Juul Holst from the University of Copenhagen identifies "enteroglucagon" (later named GLP-1) as a molecule that enters the bloodstream from the gut and regulates blood sugar

Whether you inject at 8:00 AM or 8:00 PM, the steady state of the medication in your bloodstream remains relatively constant over the week

doi: 10.1021/acs.jmedchem.9b01953 121 WagnerSBrierleyDILeeson-PayneAJiangWChianeseRLamBYHet al

These include irritable bowel syndrome, stomach ulcers, appendicitis, and Crohn's disease

After absorption into the bloodstream, it binds to GLP-1 receptors located in key areas of the brain involved in appetite control, as well as in the gastrointestinal tract
