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For most individuals, GLP-1-related fatigue improves within two to four weeks after starting treatment

The current study focused on the onemonth follow-up because it was the first follow-up time point available in this dataset for most participants and provided indication of short-term change in food noise, concluded investigators

2025 Europe PMC Efficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial

Participants were recruited through ResearchMatch and snowball sampling

Further, 34.7% achieved 25% loss, and 19.3% achieved 30% loss

[DOI] [PubMed] [Google Scholar] 60.Gera A., Latif F., Borra V., Naz S., Mittal V., Ayoobkhan F.S., et al