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The goal of obesity treatment is improving health, Dr
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Free-text responses highlighted that the American Diabetes Association (ADA) guidelines provide clear recommendations on the prioritisation of SGLT2is versus GLP-1 RAs for adults with CKD and T2D
Thus, insulin resistance provides a key mechanistic link between MASLD and HFpEF through lipotoxicity, altered energy metabolism, and microvascular injury
GLP-1s increased the release of insulin but had an extremely short half-life (one to two minutes), making them highly unfavorable as a treatment for diabetes
GLP-1 medications typically cause nausea, which decreases over time as the body adjusts, and they have an established safety profile in both diabetes and weight loss applications across millions of patients
