sglt2 inhibitors vs glp 1 agonists Effect of combination treatment with glucagon-like peptide-1 receptor and sodium-glucose cotransporter-2 on incidence of cardiovascular and serious renal events: population based cohort study Cardiorenal Protection: Potential of SGLT2

Just to catch anyone up who is unfamiliar with the term GLP-1 agonist, this term refers to a class of medications that all act on the GLP-1 receptor

For patients primarily seeking weight management, either with or without type 2 diabetes, higher-dose formulations such as semaglutide 2.4 mg (Wegovy) or liraglutide 3 mg (Saxenda) may be more appropriate

CKD, chronic kidney disease

Moreover, a favorable impact of GLP-1RAs on cardiac remodeling can occur through activation of the eNOS/cyclic guanosine monophosphate (cGMP)/protein kinase G (PKG) nexus [72]

It may also help through weight loss, since losing weight can improve insulin resistance

doi: 10.1111/dom.16316