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Mecanismo central: como os GLP-1 agonistas reduzem o apetite

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This is particularly important for newer entrants, where published clinical evidence may still be limited

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In addition to SGLT2 inhibitors and GLP-1 receptor agonists, finerenone, a nonsteroidal mineralocorticoid receptor antagonist, has demonstrated significant cardiovascular and kidney-protective effects in people with type 2 diabetes mellitus and CKD or HF [129-132]