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Description
Persistent hunger typically reflects suboptimal dose, genetic variation in GLP-1 receptor sensitivity, or behavioral factors like eating too quickly or choosing calorie-dense foods

This can lead to decreased appetite and weight loss
Consistent with these observations, patients included in the studies analyzed in this systematic review frequently reported significant cardiometabolic benefits in addition to BW loss

doi: 10.1001/jama.2020.4249

Instead, clinicians and patients weigh: - Goals: Is the aim modest loss for joint pain relief or large loss for metabolic disease prevention

Therefore, it is recommended to start the medication at a very low dose (1 mg or 2 mg) to help your body adjust, improve tolerance, and reduce the risk of side effects
