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Remarkably, 60% of participants achieved at least 20% weight loss, and 23% lost 30% or more of their body weight

Dual benefits for type 2 diabetes or obesity-related heart risks

However, it is important to emphasize that tirzepatide is not approved for, nor specifically designed to treat, autoimmune diseases

Its unique pharmacokinetic properties, including predominantly non-renal elimination, make it suitable for patients with renal and hepatic impairments without dose adjustment

While the list of pathophysiologic defects continues to grow, the ominous octet provides a representation of 8 key defects found in T2DM ( Figure 1 )